Yes, it does seem to be a luck of the draw thing. As a 2016 SL owner (stock, no mods albeit with only 20,000 miles on it--it is not a daily driver) I have had no problems--yet perhaps. It is clear there can be problems with EGR's (even if deleted--they made a change in 2017 to the EGR to beef it up a slight bit--2016's can have problems earlier..) and the DPF, SCR and DEF systems have a lot of electronics and things that can go wrong. Polyanna to think otherwise. Are deletes the answer? Opinions vary, but it is hard to deny that eliminating the DPF, SCR and DEF system takes a lot of potential problem areas out of the equation.
Hard to argue with regular fuel filter changes using Fleetguard OEM or a quality filter--don't exceed 10000 miles. Also, consider using a lubricity additive such as Diesel Kleen or others--many threads and opinions on that here. Keeping the HP fuel pump lubricated and those piezo injectors clean cannot be bad thing Also, if stock, consider lowering your oil change interval. All that soot and high temps....will it keep you from spinning a bearing? Who knows, but it is cheap insurance.
All you really can control is clean fuel and oil, and other fluids. Right? Enjoy--they are fun, super comfortable trucks to drive.